<International Circulation>:  What are the advantages and disadvantages for the use of IVUS (Intravascular ultrasound)? 
    Prof Eckhart Fleck: The shortcomings with IVUS is that it is invasive， it is quite a large catheter and also quite expensive to perform. Since it also a stiff catheter you may encounter problems with diseased vessels in terms of spasms.  Sometimes you cannot distinguish between diseased vessels and the stenosis by which you create from the catheter but momentarily it is the only device which can be used. In the future we will combine it with optical coherence tomography (OCT) which will allow us to see more clearly from the inside surface of the artery. This is very useful but for the future we need more information besides only on the surface; for example if there is a rupture or not? This we can already see very clearly with the OCT very well. We would like to find out more information about the reasons for the rupture and for that we need specific binding， specific contrast and specific pictures. 

 《国际循环》：IVUS的优势和不足是什么？
    Fleck教授：IVUS的不足是有创性，需要放置大口径的导管，同时花费也很高。由于导管较硬，可能会遇到病变血管发生痉挛的问题。在某些情况下，我们无法区分病变血管和导管所引起的管腔狭窄，但是当前IVUS是唯一选择。在未来，我们应当联合应用IVUS和光学相干成像（OCT），这样我们就能更加清楚地观察动脉的内壁。这很有用处，不过在未来我们还要获取更多信息，不只是血管壁的情况。比如，我们还可以确定有没有血管破裂，应用OCT我们可以很好地观察。我们还想了解血管破裂原因的更多信息，为了实现这一目的，我们需要特异性的结合、特定的对比剂和图像。

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